Autoantibodies in Neurology

Autoantibodies in Neurology

Neurological disorders presenting symptoms such as memory loss, confusion, hallucinations, and seizures may be caused by underlying autoimmune diseases.

In neurological conditions that are difficult to diagnose, such as anti-NMDAR encephalitis, paraneoplastic syndromes (PNS), or neuromyelitis optica, testing for autoantibodies can be helpful.

The Germano de Sousa Center for Laboratory Medicine, a reference center for autoimmunity, offers a comprehensive panel of tests for the detection of 32 autoantibodies in serum and/or CSF.

Autoimmune Diseases

Autoimmune Encephalitis

• Anti-NMDAR
• Anti-VGKC (LGI1, CASPR2),
• Anti-GABAR,
• Anti-AMPAR
• Anti-DPPX

Optic neuromyelitis

• NMO-IgG / anti-AQP4

Myasthenia Gravis

• Anti-acetylcholine receptor
• Anti-MuSK
• Anti-titin
• Anti-RyR

Stiff-person syndrome (stiff-man)

• Anti-Amphiphysin
• Anti-GAD

Polyneuropathies

• Anti-GM1
• Anti-GM2
• Anti-GM3
• Anti-GD1a
• Anti-GD1b
• Anti-GT1b
• Anti-GQ1b
• Anti-MAG

Paraneoplastic Syndrome

• Anti-Hu
• Anti-Ri
• Anti-Yo
• Anti-Tr
• Anti-Ma1 (PNMA1)
• Anti-Ma2/Ta (PNMA2)
• Anti-Amphiphysin
• Anti-GAD
• Anti-CV2
• Anti-NMDAR
• Anti-SOX1
• Anti-AMPAR
• Anti-GABAR
• Anti-VGKC
• Anti-recoverin
• Anti-titin
• Anti-Zic4

Download the brochure