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Food intolerance

Food intolerance

Find out which substances you are intolerant to by taking a food intolerance test.

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What is food intolerance?

Intolerance is defined as any mechanism that cannot be identified as a “true” allergic reaction (which is IgE-mediated) and includes immune reactions that are difficult to link to a specific food, but whose moderate pathological effects can trigger a series of nonspecific symptoms, such as:

  • Excess weight
  • Digestive disorders: diarrhea, irritable bowel syndrome, cramps, bloating, flatulence, heartburn…
  • Skin manifestations: irritation, acne, psoriasis…
  • Headaches: migraines, nausea…
  • Psychological disorders: anxiety, depression, fatigue…
  • Respiratory disorders
  • Others: arthritis, joint inflammation…

How to Prevent It

Find out which substances you are intolerant to by undergoing a food intolerance test.

Check to see if your body exhibits unusual reactions after eating certain foods.

Avoid eating foods that may cause food intolerance.

Food Intolerance and Weight Management

Approximately 20 to 35% of the population suffers from various clinical manifestations resulting from IgG-mediated intolerance to different foods. These manifestations appear later and are less obvious; as a result, they may go unnoticed and undiagnosed for quite some time.

Significant weight loss has been observed in people prone to being overweight when they follow a diet that eliminates foods identified as prohibited through an intolerance diagnosis.

What does the food intolerance test involve?

Food intolerance corresponds to a Type III hypersensitivity reaction, in which circulating immune complexes are formed, mediated by specific IgG (IgG4).

The food hypersensitivity reaction that culminates in the production of IgG4 is rooted in poor food tolerance to a certain food group, which cannot be completely digested, likely due to an enzymatic deficiency in the digestive system. As a result, polypeptides are produced that the body recognizes as foreign substances, triggering a food sensitivity reaction.

The Food Intolerance test is a laboratory test that detects abnormal serum levels of IgG4 (proteins associated with sensitivity, not allergy), produced in response to a wide variety of foods.

Food allergy, as it is more commonly known, is based on a pathophysiological reaction mediated by specific IgE in response to an allergen.

The main food intolerances are to lactose and gluten.

Recommendations for Taking the Test

  • Do not take the test during an acute infection.
  • If you are taking acetylsalicylic acid, do not take the test until at least 2 days after stopping the medication.
  • If necessary, take into account cortisone and corticosteroid levels to ensure they do not affect the results.
  • It is not necessary to fast before the blood collection.

What Is Food Intolerance?

Results Information

Here is an example of how the edited results of the Food Intolerance Assessment are presented, classified as follows:

Eliminate (+++)

The presence of high reactivity to these foods against IgG antibodies indicates the existence of an active, inflamed, and leaky gut. It is advisable to completely eliminate these foods from the diet for a period of time (one year) and to evaluate and treat the possible causes.

Rotate (++)

Presence of a moderate level of IgG antibodies against these foods.
It is advisable to completely eliminate these foods from the diet for an extended period (one year). Symptom improvement typically occurs within a few weeks after starting the diet.

Restrictions exist (+)

The presence of a low level of IgG antibodies at the threshold or “borderline” level, which is interpreted as low sensitivity to these foods.
This could be due to past or very recent immunity, or a phase increase.
The existence of cross-reactions with other antibodies cannot be ruled out.

Absence of a reaction

No IgG antibodies to the proteins of these foods were detected. Their consumption is permitted without restrictions, unless there is unnoticed interference with other necessary diets (diabetes, gout, biologics).

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Test example

germanodesousa Intolerância alimentar
germanodesousa Intolerância alimentar

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CLINICAL PATHOLOGY LABORATORY

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